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Source document· January 26, 2026

UPS (UPS) Q1 2025 Earnings Call Transcript

View original at nasdaq.com
UPS (UPS) Q1 2025 Earnings Call Transcript Image source: The Motley Fool. DATE Tuesday, April 29, 2025 at 8:30 a.m. ET CALL PARTICIPANTS Chief Executive Officer — Carol TomeChief Financial Officer — Brian DykesPresident, U.S…
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  • The world hasn't faced such enormous potential impacts to trade in more than 100 years

    80% confidence
  • UPS has built in chaos costs to manage volume and maintain service during Q2 facility closures, impacting margin improvement

    80% confidence
  • The only certainty is that UPS doesn't know which scenario will play out for full-year outlook

    80% confidence
  • China-to-rest-of-world volume expected up 40% in Q2 2025

    80% confidence
  • Supply Chain Solutions revenue expected down approximately $500M in Q2 2025 due to Coyote divestiture

    80% confidence
  • International revenue expected down approximately 2% in Q2 2025

    80% confidence
  • Uncertainty surrounding global trade policies and other matters led to a drop in consumer confidence and muted demand in February-March 2025

    80% confidence
  • U.S. Domestic operating margin expected up approximately 30 bps to approximately 9.3% in Q2 2025

    80% confidence
  • Many UPS SMB customers are 100% single-sourced from China, causing uncertainty due to 145% tariff announcement

    80% confidence
  • UPS ultimate target is 400 facilities partially or fully automated with 200 facilities closed

    80% confidence
  • 95% of small package customers expect to maintain current shipping models despite tariffs

    80% confidence
  • U.S. ADV expected down approximately 9% in Q2 2025

    80% confidence
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Late-2026 Biotech Catalyst Season: FDA Decisions and Pivotal Readouts Converge Across Oncology, Hepatology and Cardiometabolic
Mid-November 2026 is dense with scheduled biotech catalysts. The ivonescimab BLA PDUFA date is 2026-11-14, the lorundrostat PDUFA date is 2026-12-22, and Phase 3 ECLIPSE hepatitis delta data are due in Q1 2027. Alongside these, siRNA and antibody programs (plozasiran, elebsiran/tobevibart, ianalumab, nipocalimab) reported or presented data at AHA, AASLD, ACR and ASH, while Oryzon advanced iadademstat in AML with Spanish trial authorizations and a planned ALICE-3 Phase III. Late-stage data and regulatory milestones are driving the sentiment. A planned delisting (EGM 2026-11-19, application 2027-01-25) is a separate corporate-structure event with no clear link to the rest.
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EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Padrões que observamos ›
Onde as fontes divergem
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
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UPS (UPS) Q1 2025 Earnings Call Transcript — Source | Via News | pt.VIA.NEWS