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Source document· December 16, 2025

Eli Lilly or Merck: Where Should Investors Put Their Money?

View original at finance.yahoo.com
Eli Lilly or Merck: Where Should Investors Put Their Money? Eli Lilly LLY and Merck MRK are both major global pharmaceutical companies with blockbuster drug portfolios and deep pipelines…
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  • There are rising concerns about Merck's ability to grow its non-oncology business ahead of the upcoming loss of exclusivity of Keytruda in 2028.

    80% confidence
  • Keytruda's sales are expected to remain strong until its 2028 patent exclusivity expiration.

    80% confidence
  • Eli Lilly plans to file regulatory applications for orforglipron in obesity later this year, setting up the timeline for a potential launch next year.

    80% confidence
  • Eli Lilly expects its new drugs (Mounjaro, Zepbound, Omvoh, Jaypirca, Ebglyss and Kisunla), along with expanded use of existing drugs, to drive sales growth in 2026.

    80% confidence
  • An oral pill like orforglipron has the potential to be a more convenient alternative to injectable treatments like Zepbound and rival Novo Nordisk's Wegovy.

    80% confidence
  • Despite its expensive valuation, Lilly is clearly a much better pick than Merck, given its significant price appreciation, product and pipeline portfolio in high-growth therapeutic areas like obesity, robust growth prospects and bullish analyst sentiment.

    80% confidence
  • Competitive pressure might increase for Keytruda in the near future from dual PD-1/VEGF inhibitors like Summit Therapeutics' ivonescimab.

    80% confidence
  • Keytruda contributes more than 50% of Merck's pharmaceutical sales.

    80% confidence
  • Oncology drives more than 60% of Merck's total revenues.

    80% confidence
  • Merck's new products Capvaxive and Winrevair have the potential to generate significant revenues over the long term and help fill the potential revenue gap created by Keytruda's upcoming LOE.

    80% confidence
  • GLP-1 drugs Mounjaro and Zepbound account for around 36% of Eli Lilly's total revenues.

    80% confidence
  • Merck positioned to launch around 20 new vaccines and drugs over the next few years, with many having blockbuster potential.

    80% confidence

Data points we hold from this source

Merck & Co., Inc. · eps estimate 20268.70 USD
Merck & Co., Inc. · eps estimate 20258.97 USD