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Source document· December 17, 2025

KEYTRUDA® (pembrolizumab) Plus Padcev® (enfortumab vedotin-ejfv) Significantly Improved Event-Free Survival, Overall Survival and Pathologic Complete Response Rates for Cisplatin-Eligible Patients with MIBC When Given Before and After Surgery

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KEYTRUDA® (pembrolizumab) Plus Padcev® (enfortumab vedotin-ejfv) Significantly Improved Event-Free Survival, Overall Survival and Pathologic Complete Response Rates for Cisplatin-Eligible Patients with MIBC When Given Before and After Surgery First and only immunotherapy plus ADC regimen, used perioperatively, to exten…

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The KEYNOTE-B15/EV-304 trial results represent a potential advancement for cisplatin-eligible patients with muscle-invasive bladder cancer
80% confidence
The KEYNOTE-B15/EV-304 trial results are encouraging as nearly 50% of patients treated with standard neoadjuvant cisplatin-based chemotherapy and surgery experience recurrence
80% confidence